automatic features recognition for anthropometry

Abstract For the purpose of reducing uncertainties in the measurements of morphologically complex biological objects, the authors present a new automatic method, which takes advantage from the representation of the object in the form of the 3D geometric model obtained from CT-scans or 3D scanning. In this paper, the method is verified in real cases and compared with the traditional approaches

Revisión de los métodos computerizados para la reconstrucción de fragmentos arqueológicos de cerámica

[ES] Las cerámicas son los hallazgos más numerosos encontrados en las excavaciones arqueológicas; a menudo se usan para obtener información sobre la historia, la economía y el arte de un sitio. Los arqueólogos rara vez encuentran jarrones completos; en general, están dañados y en fragmentos, a menudo mezclados con otros grupos de cerámica.El análisis y la reconstrucción de fragmentos se realiza por un operador experto mediante el uso del método manual tradicional. Los artículos revisados proporcionaron evidencias de que el método tradicional no es reproducible, no es repetible, consume mucho tiempo y sus resultados generan grandes incertidumbres. Con el objetivo de superar los límites anteriores, en los últimos años, los investigadores han realizado esfuerzos para desarrollar métodos informáticos que permitan el análisis de fragmentos arqueológicos de cerámica, todo ello destinado a su reconstrucción. Para contribuir a este campo de estudio, en este artículo, se presenta un análisis exhaustivo de las publicaciones disponibles más importantes hasta finales de 2019. Este estudio, centrado únicamente en fragmentos de cerámica, se realiza mediante la recopilación de artículos en inglés de la base de datos Scopus, utilizando las siguientes palabras clave: "métodos informáticos en arqueología", "arqueología 3D", "reconstrucción 3D", "reconocimiento y reconstrucción automática de características", "restauración de reliquias en forma de cerámica ". La lista se completa con referencias adicionales que se encuentran a través de la lectura de documentos seleccionados. Los 53 trabajos seleccionados se dividen en tres períodos de tiempo. Según una revisión detallada de los estudios realizados, los elementos clave de cada método analizado se enumeran en función de las herramientas de adquisición de datos, las características extraídas, los procesos de clasificación y las técnicas de correspondencia. Finalmente, para superar las brechas reales, se proponen algunas recomendaciones para futuras investigaciones.[EN] Potteries are the most numerous finds found in archaeological excavations; they are often used to get information about the history, economy, and art of a site. Archaeologists rarely find complete vases but, generally, damaged and in fragments, often mixed with other pottery groups. By using the traditional manual method, the analysis and reconstruction of sherds are performed by a skilled operator. Reviewed papers provided evidence that the traditional method is not reproducible, not repeatable, time-consuming and its results have great uncertainties. To overcome the aforementioned limits, in the last years, researchers have made efforts to develop computer-based methods for archaeological ceramic sherds analysis, aimed at their reconstruction. To contribute to this field of study, in this paper, a comprehensive analysis of the most important available publications until the end of 2019 is presented. This study, focused on pottery fragments only, is performed by collecting papers in English by the Scopus database using the following keywords: “computer methods in archaeology", "3D archaeology", "3D reconstruction", "automatic feature recognition and reconstruction", "restoration of pottery shape relics”. The list is completed by additional references found through the reading of selected papers. The 53 selected papers are divided into three periods of time. According to a detailed review of the performed studies, the key elements of each analyzed method are listed based on data acquisition tools, features extracted, classification processes, and matching techniques. Finally, to overcome the actual gaps some recommendations for future researches are proposed.Highlights:The traditional manual method for reassembling sherds is very time-consuming and costly; it also requires a great deal effort from skilled archaeologists in repetitive and routine activities.Computer-based methods for archaeological ceramic sherds reconstruction can help archaeologists in the above-mentioned repetitive and routine activities.In this paper, the state-of-the-art computer-based methods for archaeological ceramic sherds reconstruction are reviewed, and some recommendations for future researches are proposed.Eslami, D.; Di Angelo, L.; Di Stefano, P.; Pane, C. (2020). Review of computer-based methods for archaeological ceramic sherds reconstruction. 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Medical Imaging of Microrobots: Toward In Vivo Applications

Medical microrobots (MRs) have been demonstrated for a variety of non-invasive biomedical applications, such as tissue engineering, drug delivery, and assisted fertilization, among others. However, most of these demonstrations have been carried out in in vitro settings and under optical microscopy, being significantly different from the clinical practice. Thus, medical imaging techniques are required for localizing and tracking such tiny therapeutic machines when used in medical-relevant applications. This review aims at analyzing the state of the art of microrobots imaging by critically discussing the potentialities and limitations of the techniques employed in this field. Moreover, the physics and the working principle behind each analyzed imaging strategy, the spatiotemporal resolution, and the penetration depth are thoroughly discussed. The paper deals with the suitability of each imaging technique for tracking single or swarms of MRs and discusses the scenarios where contrast or imaging agent's inclusion is required, either to absorb, emit, or reflect a determined physical signal detected by an external system. Finally, the review highlights the existing challenges and perspective solutions which could be promising for future in vivo applications

Novel Antimicrobial Strategies to Prevent Biofilm Infections in Catheters after Radical Cystectomy: A Pilot Study

Catheter-associated infections in bladder cancer patients, following radical cystectomy or ureterocutaneostomy, are very frequent, and the development of antibiotic resistance poses great challenges for treating biofilm-based infections. Here, we characterized bacterial communities from catheters of patients who had undergone radical cystectomy for muscle-invasive bladder cancer. We evaluated the efficacy of conventional antibiotics, alone or combined with the human ApoB-derived antimicrobial peptide r(P)ApoBLAla, to treat ureteral catheter-colonizing bacterial communities on clinically isolated bacteria. Microbial communities adhering to indwelling catheters were collected during the patients' regular catheter change schedules (28 days) and extracted within 48 h. Living bacteria were characterized using selective media and biochemical assays. Biofilm growth and novel antimicrobial strategies were analyzed using confocal laser scanning microscopy. Statistical analyses confirmed the relevance of the biofilm reduction induced by conventional antibiotics (fosfomycin, ceftriaxone, ciprofloxacin, gentamicin, and tetracycline) and a well-characterized human antimicrobial peptide r(P)ApoBLAla (1:20 ratio, respectively). Catheters showed polymicrobial communities, with Enterobactericiae and Proteus isolates predominating. In all samples, we recorded a meaningful reduction in biofilms, in both biomass and thickness, upon treatment with the antimicrobial peptide r(P)ApoBLAla in combination with low concentrations of conventional antibiotics. The results suggest that combinations of conventional antibiotics and human antimicrobial peptides might synergistically counteract biofilm growth on ureteral catheters, suggesting novel avenues for preventing catheter-associated infections in patients who have undergone radical cystectomy and ureterocutaneostomy

Open Government Data: Fostering Innovation

The provision of public information contributes to the enrichment and enhancement of the data produced by the government as part of its activities, and the transformation of heterogeneous data into information and knowledge. This process of opening changes the operational mode of public administrations, leveraging the data management, encouraging savings and especially in promoting the development of services in subsidiary and collaborative form between public and private entities. The demand for new services also promotes renewed entrepreneurship centred on responding to new social and territorial needs through new technologies. In this sense we speak of Open Data as an enabling infrastructure for the development of innovation and as an instrument to the development and diffusion of Innovation and Communications Technology (ICT) in the public system as well as creating space for innovation for businesses, particularly SMEs, based on the exploitation of information assets of the territory. The Open Data Trentino Project has initiated and fosters the process of opening of public information and develops as a natural consequence of this process of openness, the creation of innovative services for and with the citizens. In this paper we present how our project acts on long-chain, from raw data till reusable meaningful and scalable knowledge base that leads to the production of data reuse through the implementation of services that will enhance and transform the data into information capable of responding to specific questions efficiency and innovation

Italian Physicians' Perceptions about the Role of Asciminib in Later Lines Chronic Myeloid Leukemia in Clinical Practice: A GIMEMA Survey

Unmet needs remain in later lines chronic myeloid leukemia (CML): the response rate and the overall survival of resistant patients in the chronic phase who changed a second-generation TKI in the second line with another TKI with similar action are usually poor, while the off-target toxicities and the potential development of mutations increase. The recent approval of asciminib, a STAMP inhibitor, in the third line, has the potential to soon change the therapeutic algorithm for this subset of patients. Here, we report the results of a GIMEMA survey assessing the number of patients currently treated in the third line in Italy, the current approach in later lines by Italian physicians, and the future role of this drug according to the reason to switch to asciminib (resistance and/or intolerance), as well as the perceptions about the future position of this agent

Implicit learning deficit in children with Duchenne muscular dystrophy: Evidence for a cerebellar cognitive impairment?

This study aimed at comparing implicit sequence learning in individuals affected by Duchenne Muscular Dystrophy without intellectual disability and age-matched typically developing children. A modified version of the Serial Reaction Time task was administered to 32 Duchenne children and 37 controls of comparable chronological age. The Duchenne group showed a reduced rate of implicit learning even if in the absence of global intellectual disability. This finding provides further evidence of the involvement of specific aspects of cognitive function in Duchenne muscular dystrophy and on its possible neurobiological substrate

Timed rise from floor as a predictor of disease progression in Duchenne muscular dystrophy: An observational study

The role of timed items, and more specifically, of the time to rise from the floor, has been reported as an early prognostic factor for disease progression and loss of ambulation. The aim of our study was to investigate the possible effect of the time to rise from the floor test on the changes observed on the 6MWT over 12 months in a cohort of ambulant Duchenne boys.A total of 487 12-month data points were collected from 215 ambulant Duchenne boys. The age ranged between 5.0 and 20.0 years (mean 8.48 ±2.48 DS).The results of the time to rise from the floor at baseline ranged from 1.2 to 29.4 seconds in the boys who could perform the test. 49 patients were unable to perform the test at baseline and 87 at 12 month The 6MWT values ranged from 82 to 567 meters at baseline. 3 patients lost the ability to perform the 6mwt at 12 months. The correlation between time to rise from the floor and 6MWT at baseline was high (r = 0.6, p<0.01).Both time to rise from the floor and baseline 6MWT were relevant for predicting 6MWT changes in the group above the age of 7 years, with no interaction between the two measures, as the impact of time to rise from the floor on 6MWT change was similar in the patients below and above 350 m. Our results suggest that, time to rise from the floor can be considered an additional important prognostic factor of 12 month changes on the 6MWT and, more generally, of disease progression